Science in Transition: Study Reveals Reproducibility Problems!
International study by Bielefeld University shows how analytical methods vary scientific results. Reproducibility in focus.

Science in Transition: Study Reveals Reproducibility Problems!
On March 9, 2025, a major international study was published examining the influence of analytical methods on scientific results. Researchers from Bielefeld University, together with over 300 scientists from various institutions, analyzed 174 independent studies to question the reproducibility and reliability of scientific results. The findings were published in the specialist journalBMC Biologypublished and raise fundamental questions about the quality of scientific practices.
The results of this study show that different analytical methods can lead to widely varying conclusions. This highlights not only the complexity of data analysis, but also the need for more transparent research practices. A central concern of researchers is the promotion of replication studies to ensure the validity of research results. The study was conducted on February 6, 2025BMC Biologypublished and is considered a milestone for reflected and transparent research practice.
Relevance to the scientific community
The pitfalls in the reproducibility of scientific results are well documented in many disciplines. Previous studies, including those by Baker (2016) and Bohannon (2015), have shown that much research, particularly in psychology and economics, cannot be replicated. This current investigation also addresses the need to standardize the documentation of the methods used to ensure transparency of the results.
A sub-project of the Collaborative Research Center TRR 212 (“NC³”) supports this through targeted training for scientists in early career phases that deal with meta-analyses and transparency in research. Researchers at Bielefeld University are also members of the Society for Open, Reliable and Transparent Ecology and Evolutionary Biology (SORTEE), which advocates for these principles.
Sustainable impact on research
The study highlights the importance of replication studies, which are considered necessary to restore confidence in scientific results. This topic has already had a significant impact on scientific disciplines in the past and could become even more important in the future. The significant variation in the results of the studies analyzed highlights the challenges facing the scientific community.
In the context of current discussions about reproducibility and academic integrity, this study is not only relevant to ecological and evolutionary biology, but also represents an impetus for all research areas that have to deal with the validity of their results. Another aspect highlighted is the need for fundamental reform towards transparent and reproducible research practices.